(187)Diphenyl Derivatives. II.

Univalent Functions with Univalent Derivatives. Ii

The structure of manumycin. II. Derivatives.

Derivatives of manumycin (1) were obtained by acetylation and reduction, respectively, and characterized by their spectroscopic data. Structure-activity relationships of the antibiotic were discussed.

Phloroglucinol Derivatives as Potent Photosystem II Inhibitors

Studies on structure/activity relationships o f phloroglucinol derivatives tha t had been de­ signed based on the structures o f grandinol and hom ograndinol. potent photosystem II (PS II) inhibitors in Eucalyptus grandis, revealed th a t two electron-withdraw ing groups which differ by their electron-w ithdraw ing pow er on a phloroglucinol nucleus were essential for activity. A larger differe...

Copper(II) Complexes of Hydrazone Derivatives

P. Souza* 3, M. A. Mendiola3, A. Arquerob, V. Fernández3, E. Gutiérrez-Pueblac, C. Ruiz-Valeroc a Departamento de Quimica (C -V III), Facultad de Ciencias, Universidad Autonoma de Madrid, Cantoblanco, 28049-Madrid, Spain b Departamento A.T.S.I., Facultad de Informätica, Universidad Politecnica de Madrid, M ontegancedo s/n, 28660-Boadilla del Monte, Madrid, Spain c Instituto de Ciencias de Mater...

Photosystem II Inhibition by Pyran-enamine Derivatives

Through the studies on structure-activity relationships o f 5-acyl-3-(l-aminoalkylidene)4-hydroxy-2 H-pyran-2,6(3 H)-dione derivatives in photosystem II (PS II) inhibition, overall lipophilicity o f the molecule was found to be a major determinant for the activity. In the sub­ stituted N-benzyl derivatives, not only the lipophilicity but also the electronic and steric char­ acters o f the subst...